
Cosmetic peptide
SNAP-8 Acetyl Octapeptide-3
Cosmetic peptide
SNAP-8 research overview
- CAS Number
- 868844-74-0
- Molecular Formula
- C₄₁H₇₀N₁₆O₁₆S
- HPLC Purity
- ≥99% (batch-verified)
- Form
- Lyophilised powder
- Storage
- 2–8°C, desiccated, protected from light
- Classification
- Research reagent - in vitro use only
SNAP-8 (acetyl octapeptide-3) is a synthetic eight-amino-acid peptide modelled on the N-terminal end of SNAP-25, one of the three proteins that form the SNARE complex. It is an elongated version of the hexapeptide Argireline and is used in cosmetic-science and cell-biology research on vesicle fusion.
The SNARE complex, formed by SNAP-25, syntaxin and synaptobrevin (VAMP), drives the fusion of synaptic vesicles with the cell membrane. Short peptides that mimic part of SNAP-25 can compete with the full-length protein for a place in the complex. SNAP-8 extends the six-residue Argireline sequence by two residues at the C-terminus.
In in vitro research, SNAP-8 is studied in SNARE complex assembly assays, where it is reported to destabilise complex formation, and in cultured neuronal and neuroendocrine cell models, where calcium-dependent neurotransmitter release is measured. It is also used as a reference material in formulation and analytical work on cosmetic peptides.
SNAP-8 is studied alongside other cosmetic-science peptides such as GHK-Cu. Velox Peptides supplies SNAP-8 at ≥99% HPLC-verified purity as a 10mg lyophilised research reagent. Not for human or veterinary consumption.
Summary paraphrased from the peer-reviewed preclinical literature. For in vitro research use only. For source citations, email support@veloxpeps.com.
SNAP-8 Research Hub
Technical data
Compound specifications
| Common name | SNAP-8 (Acetyl octapeptide-3, Acetyl glutamyl heptapeptide-1) |
|---|---|
| Full name | Acetyl octapeptide-3 |
| CAS number | 868844-74-0 |
| Molecular formula | C₄₁H₇₀N₁₆O₁₆S |
| Molecular weight | 1075.2 g/mol |
| Sequence | Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2 |
| HPLC purity | ≥99% (batch-verified) |
| Appearance | White to off-white lyophilised powder |
| Solubility | Bacteriostatic water, sterile saline |
| Storage (lyophilised) | 2–8°C, protected from light |
| Storage (reconstituted) | 2–8°C, up to 28 days |
| Supplied as | 10mg |
Purity & documentation
Batch testing and certificate of analysis
Every batch of SNAP-8 is third-party HPLC-tested prior to dispatch. Batch documentation is available on request.
Previous batch CoAs are archived in the CoA library. For batch-specific CoA requests prior to purchase, contact support@veloxpeps.com.
Delivery & payment
Buying SNAP-8 in the UK
SNAP-8 is sold by Velox Peptides (CRP Labs Ltd, UK company no. NI738125) and dispatched from the UK. Choose a vial size, pay on one page, and your order is dispatched the next working day.
- Delivery: Royal Mail Tracked 24 (1–2 working days, £5.99, free over £100) or Tracked 48 (2–3 working days, £3.80). See shipping.
- Payment: Pay by Bank through FCA-authorised open banking, or bank transfer. No card details needed.
- Testing: See the batch testing details above and past reports in the CoA library.
- Research use only: Supplied as a research reagent for in vitro use. Not for human or veterinary consumption. See our Research Use Policy.
Explore more research compounds:
No account needed
How to order
No card details required - Pay by Bank or manual bank transfer
Add to order & proceed to checkout
We email you bank details instantly
Transfer & we dispatch next working day
What purity is Velox Peptides SNAP-8?
How is SNAP-8 supplied and reconstituted for research use?
What is SNAP-8 studied for in preclinical research?
What is the CAS number for SNAP-8?
How does SNAP-8 differ from Argireline?
How quickly is my order dispatched and delivered?
How do I pay, and is it secure?
Does my order include a certificate of analysis?
Compliance notice
For in vitro research use only. SNAP-8 is supplied solely as a research reagent for qualified professionals conducting in vitro or animal-model studies. It is not a medicinal product within the meaning of the Human Medicines Regulations 2012. It has not been evaluated by the MHRA or FDA. It is not intended for human or veterinary consumption, diagnosis, treatment, cure, or prevention of any condition. Any use outside lawful scientific research is outside the scope of sale.
Research bulletin
Free Researcher’s Handbook + 10% off
New compound arrivals, batch-release notices and plain-language research summaries, plus our reconstitution, storage & CoA handbook (PDF) and a 10% off code for your first research order.
For researchers only. Unsubscribe at any time. We never share your address.