STACK IMAGE - RESEARCH BUNDLE · 3 COMPOUNDS
Angiogenic Repair Research Bundle
BPC-157 + TB-500 + GHK-Cu
BPC-15710mg£39.99TB-50010mg£29.99GHK-Cu100mg£44.99
£109.97
£79.98
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TB-500 Thymosin Beta-4
For in vitro research use only. TB-500 is not for human or veterinary consumption, diagnosis, treatment, or prevention of any condition.
TB-500 is a synthetic version of Thymosin Beta-4, a protein found naturally in mammalian tissue. Preclinical studies have investigated how it interacts with actin - a structural protein that controls how cells move and organise themselves, particularly during tissue repair.
- CAS Number
- 77591-33-4
- Molecular Formula
- C₂₁₂H₃₅₀N₅₆O₇₈S
- HPLC Purity
- ≥99% (batch-verified)
- Form
- Lyophilised powder
- Storage
- 2–8°C, desiccated, protected from light
- Classification
- Research reagent - in vitro use only
≥99%
HPLC purity
3rd-Party Tested
Independent lab
CoA Every Order
Batch-specific
Tracked 24
Royal Mail UK
Pay by Bank
No card stored
TB-500 research overview
TB-500 is a synthetic peptide corresponding to the central active fragment of Thymosin Beta-4 (Tβ4), a 43-amino-acid protein that is one of the most abundant intracellular peptides found in mammalian cells. Thymosin Beta-4 is involved in regulating actin polymerisation — the process by which actin monomers assemble into filaments that form the structural scaffolding of cells and drive cell motility. TB-500 isolates the LKKTET actin-binding sequence from within the full Thymosin Beta-4 structure, providing a more tractable synthetic tool for studying these mechanisms in isolation.
Preclinical studies on TB-500 and the broader Thymosin Beta-4 family have primarily examined tissue closure mechanics, angiogenesis, and cellular repair. In rodent models, researchers have investigated how Tβ4-derived peptides affect the migration of cell types — including endothelial cells, keratinocytes, and fibroblasts — into repair sites, where directed cell movement is critical for tissue closure. Angiogenesis studies have examined the role of this peptide family in promoting new blood vessel formation into ischaemic or damaged tissue. Research has also looked at its effects on inflammatory markers in experimentally induced injury models.
TB-500 is frequently studied alongside BPC-157 in multi-compound preclinical protocols, as the two peptides are understood to act on complementary repair-associated pathways — BPC-157 primarily through VEGF and growth hormone receptor signalling, and TB-500 through actin-mediated cell motility. This complementarity has made the BPC-157 + TB-500 pairing a common combination in tissue repair research. Velox Peptides supplies TB-500 at ≥99% HPLC-verified purity as a lyophilised research reagent for in vitro use. Not for human or veterinary consumption.
Summary paraphrased from the peer-reviewed preclinical literature. For in vitro research use only. For source citations, email support@veloxpeps.com.
📖 TB-500 Research Hub
Compound specifications
| Common name | TB-500 |
|---|---|
| Full name | Thymosin Beta-4 |
| CAS number | 77591-33-4 |
| Molecular formula | C₂₁₂H₃₅₀N₅₆O₇₈S |
| Molecular weight | 4963.4 g/mol |
| Sequence | Ac-SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES-OH (frag) |
| HPLC purity | ≥99% (batch-verified) |
| Appearance | White to off-white lyophilised powder |
| Solubility | Bacteriostatic water, sterile saline |
| Storage (lyophilised) | 2–8°C, protected from light |
| Storage (reconstituted) | 2–8°C, up to 28 days |
| Supplied as | 10mg |
Batch testing and certificate of analysis
Every batch of TB-500 is third-party HPLC-tested prior to dispatch. Batch documentation is available on request.
Previous batch CoAs are archived in the CoA library. For batch-specific CoA requests prior to purchase, contact support@veloxpeps.com.
Stacks containing TB-500
Related compounds
Frequently Asked Research-Use Questions
What purity is Velox Peptides TB-500?
TB-500 is supplied at ≥99% HPLC-verified purity. Batch documentation is available on request.
How is TB-500 supplied and reconstituted for research use?
TB-500 is supplied as a lyophilised powder in sterile single-use vials. For in vitro research use, reconstitution is performed with bacteriostatic water. See the reconstitution calculator for volume calculations based on required concentration.
What is TB-500 used for in preclinical research?
TB-500 is studied in the peer-reviewed literature across the pathways described in the research overview above. Velox Peptides supplies TB-500 strictly as a research reagent for in vitro use by qualified researchers. It is not a medicinal product and is not for human or veterinary consumption.
What is the CAS number for TB-500?
The CAS registry number for TB-500 is 77591-33-4.
Is TB-500 legal to buy in the UK?
Yes. Research peptides including TB-500 are lawful to purchase in the United Kingdom strictly for legitimate in vitro scientific research purposes. They are not controlled substances under UK law and are not subject to prescription requirements when purchased for research use. Velox Peptides supplies TB-500 solely as a research reagent to qualified researchers. Buyers are responsible for ensuring all use complies with applicable law and with Velox Peptides’ Research Use Policy.
What is the difference between TB-500 and full Thymosin Beta-4?
Full Thymosin Beta-4 (Tβ4) is a naturally occurring 43-amino-acid protein involved in actin regulation, tissue repair, and cell signalling. TB-500 refers to the synthetic peptide fragment containing the LKKTET actin-binding region of Tβ4 — the sequence responsible for G-actin sequestration and its effects on cell motility. TB-500 is shorter, more economical to synthesise, and easier to work with in research settings than full Tβ4 while targeting the same core actin-interaction mechanism. Velox Peptides supplies TB-500 at ≥99% HPLC purity for in vitro research use.
How quickly is my order dispatched and delivered?
Orders placed before 2pm on a working day are dispatched the same day via Royal Mail Tracked 24, typically arriving in 1–2 working days, with tracking emailed on dispatch. UK shipping is free over £100, and EU shipping is available.
How do I pay, and is it secure?
We accept Pay by Bank - an instant, secure open-banking payment via Fena, where you authorise the payment in your own banking app and no card details are stored on our site. Manual UK bank transfer is available as a fallback. Orders are dispatched within 24 hours of cleared payment.
Does my order include a certificate of analysis?
Yes. Every order includes a batch-specific Certificate of Analysis documenting third-party HPLC purity and mass-spectrometry identity confirmation, emailed with your order confirmation. Previous batch CoAs are archived in our CoA library.
Compliance notice
For in vitro research use only. TB-500 is supplied solely as a research reagent for qualified professionals conducting in vitro or animal-model studies. It is not a medicinal product within the meaning of the Human Medicines Regulations 2012. It has not been evaluated by the MHRA or FDA. It is not intended for human or veterinary consumption, diagnosis, treatment, cure, or prevention of any condition. Any use outside lawful scientific research is outside the scope of sale.
