Mots-C Mots-C PRODUCT IMAGE
HPLC VERIFIED COA SUPPLIED ≥98.5% PURITY
— Metabolic

Mots-C Mitochondrial Open Reading Frame Peptide

For in vitro research use only. Mots-C is not for human or veterinary consumption, diagnosis, treatment, or prevention of any condition.

Mots-C is a small peptide (16 amino acids long) with an unusual origin: its instructions are encoded in the DNA found inside mitochondria (the parts of a cell that produce energy), not in the cell's main DNA. Under metabolic stress, studies have investigated how it travels to the cell's nucleus and activates AMPK — an enzyme that acts like a fuel gauge for the cell, sensing how much energy is available and adjusting the cell's behaviour.

CAS Number
—
Molecular Formula
16-AA mitochondrial peptide
HPLC Purity
98.5% (batch-verified)
Form
Lyophilised powder
Storage
2–8°C, desiccated, protected from light
Classification
Research reagent — in vitro use only

Research overview

Mots-C is a 16-amino-acid peptide with a unique origin. While most proteins are encoded in the DNA inside the cell nucleus, Mots-C is encoded in the DNA found inside mitochondria — the parts of a cell that convert food into usable energy (often described as the cell's power stations). Under conditions of metabolic stress — such as when the cell is low on energy — research suggests that Mots-C travels to the cell's nucleus and activates AMPK (AMP-activated protein kinase — an enzyme that acts like a fuel gauge for the cell, detecting how much energy is available and signalling the cell to adjust its behaviour accordingly). Animal studies have examined its influence on glucose metabolism (how the body processes sugar) and on the activity of genes involved in energy management. It is an active subject of research in mitochondrial biology and metabolic pathway studies. For research use only. Not for human or veterinary consumption.

Summary paraphrased from the peer-reviewed preclinical literature. Full citations will be available in the research library. For in vitro research use only.

Compound specifications

Common nameMots-C
Full nameMitochondrial Open Reading Frame Peptide
CAS number—
Molecular formula16-AA mitochondrial peptide
Molecular weight2174.5 g/mol
SequenceMRWQEMGYIFYPRKLR
HPLC purity98.5% (batch-verified)
AppearanceWhite to off-white lyophilised powder
SolubilityBacteriostatic water, sterile saline
Storage (lyophilised)2–8°C, protected from light
Storage (reconstituted)2–8°C, up to 28 days
Supplied as10mg

Batch testing and certificate of analysis

Every batch of Mots-C is third-party HPLC-tested prior to dispatch. A batch-specific certificate of analysis documenting HPLC purity, mass spectrometry confirmation, and appearance is supplied with every order.

Previous batch CoAs are archived in the CoA library. For batch-specific CoA requests prior to purchase, contact veloxpeps@gmail.com.

Frequently Asked Research-Use Questions

What purity is Velox Peptides Mots-C?
Mots-C is supplied at 98.5% HPLC-verified purity. A certificate of analysis is provided with every order. Every batch is third-party tested before dispatch.
How is Mots-C supplied and reconstituted for research use?
Mots-C is supplied as a lyophilised powder in sterile single-use vials. For in vitro research use, reconstitution is performed with bacteriostatic water. See the reconstitution calculator for volume calculations based on required concentration.
What is Mots-C used for in preclinical research?
Mots-C is studied in the peer-reviewed literature across the pathways described in the research overview above. Velox Peptides supplies Mots-C strictly as a research reagent for in vitro use by qualified researchers. It is not a medicinal product and is not for human or veterinary consumption.

For in vitro research use only. Mots-C is supplied solely as a research reagent for qualified professionals conducting in vitro or animal-model studies. It is not a medicinal product within the meaning of the Human Medicines Regulations 2012. It has not been evaluated by the MHRA or FDA. It is not intended for human or veterinary consumption, diagnosis, treatment, cure, or prevention of any condition. Any use outside lawful scientific research is outside the scope of sale.

Compliance statement. Velox Peptides supplies research reagents for in vitro use by qualified researchers. Every compound is sold strictly as a research reagent. No product is a medicinal product within the meaning of the Human Medicines Regulations 2012. No product has been evaluated by the MHRA or FDA. No product is intended for human or veterinary consumption, diagnosis, treatment, cure, or prevention of any condition. Any use outside lawful scientific research is outside the scope of sale. See our Research Use Policy and MHRA Statement.