Buy CJC-1295 wo DAC UK – research peptide, HPLC-verified ≥99% purity CJC-1295 wo DAC PRODUCT IMAGE
HPLC VERIFIED CoA SUPPLIED ≥99.1% PURITY
Reviews
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CJC-1295 wo DAC Growth Hormone Releasing Factor Analogue (no DAC)

For in vitro research use only. CJC-1295 wo DAC is not for human or veterinary consumption, diagnosis, treatment, or prevention of any condition.

CJC-1295 (without DAC) is a synthetic version of a signal molecule the brain naturally uses to trigger growth hormone release. Without the DAC (Drug Affinity Complex - a chemical attachment that makes some versions last much longer in the body), this compound produces a short, sharp pulse of growth hormone - more like the natural pattern the body uses.

CAS Number
863288-34-0
Molecular Formula
C₁₅₂H₂₅₂N₄₄O₄₂
HPLC Purity
99.1% (batch-verified)
Form
Lyophilised powder
Storage
2–8°C, desiccated, protected from light
Classification
Research reagent - in vitro use only
≥99%
HPLC purity
3rd-Party Tested
Independent lab
CoA Every Order
Batch-specific
Tracked 24
Royal Mail UK
Pay by Bank
No card stored

CJC-1295 wo DAC research overview

CJC-1295 without DAC (wo DAC) is a 30-amino-acid synthetic analogue of Growth Hormone Releasing Hormone 1-29 (GHRH(1-29)) — the minimally active N-terminal fragment of endogenous GHRH responsible for receptor binding and GH secretion. It incorporates several amino acid substitutions compared to native GHRH(1-29) (sermorelin) that improve its enzymatic stability and receptor binding affinity. The designation “without DAC” (without Drug Affinity Complex) indicates the absence of a maleimidoproprionic acid (MPA) moiety that would otherwise allow covalent binding to circulating albumin for extended half-life — making CJC-1295 wo DAC a shorter-acting GHRH analogue compared to the DAC formulation.

Research on CJC-1295 wo DAC centres on growth hormone secretagogue biology — the study of compounds that stimulate growth hormone (GH) release from the anterior pituitary via the GHRH receptor (GHRHR). In preclinical animal models, GHRH analogues have been examined for their ability to stimulate pulsatile GH secretion and to examine the downstream effects on circulating IGF-1 (Insulin-like Growth Factor 1), which mediates many of GH’s anabolic and metabolic effects in peripheral tissues. The shorter half-life of CJC-1295 wo DAC makes it useful for studies requiring acute, defined GH stimulation windows rather than prolonged elevation.

As a research tool, CJC-1295 wo DAC is frequently used in studies examining GHRH receptor pharmacology, GH secretion dynamics, and pituitary function in rodent models. It is also studied alongside GHRP (growth hormone releasing peptide) compounds in combinatorial protocols, as GHRH receptor agonists and ghrelin receptor agonists act synergistically on somatotroph cells to amplify GH release. Velox Peptides supplies CJC-1295 wo DAC at 99.1% HPLC-verified purity as a lyophilised research reagent for in vitro use. Not for human or veterinary consumption.

Summary paraphrased from the peer-reviewed preclinical literature. For in vitro research use only. For source citations, email support@veloxpeps.com.

Compound specifications

Common nameCJC-1295 wo DAC
Full nameGrowth Hormone Releasing Factor Analogue (no DAC)
CAS number863288-34-0
Molecular formulaC₁₅₂H₂₅₂N₄₄O₄₂
Molecular weight3367.8 g/mol
SequenceHAIBU-Y-D-Ala-DFA-LRKVLGQLSARKLLQDIMSR-NH2 (no DAC)
HPLC purity99.1% (batch-verified)
AppearanceWhite to off-white lyophilised powder
SolubilityBacteriostatic water, sterile saline
Storage (lyophilised)2–8°C, protected from light
Storage (reconstituted)2–8°C, up to 28 days
Supplied as10mg

Batch testing and certificate of analysis

Every batch of CJC-1295 wo DAC is third-party HPLC-tested prior to dispatch. Batch documentation is available on request.

Previous batch CoAs are archived in the CoA library. For batch-specific CoA requests prior to purchase, contact support@veloxpeps.com.

Frequently Asked Research-Use Questions

What purity is Velox Peptides CJC-1295 wo DAC?
CJC-1295 wo DAC is supplied at 99.1% HPLC-verified purity. Batch documentation is available on request.
How is CJC-1295 wo DAC supplied and reconstituted for research use?
CJC-1295 wo DAC is supplied as a lyophilised powder in sterile single-use vials. For in vitro research use, reconstitution is performed with bacteriostatic water. See the reconstitution calculator for volume calculations based on required concentration.
What is CJC-1295 wo DAC used for in preclinical research?
CJC-1295 wo DAC is studied in the peer-reviewed literature across the pathways described in the research overview above. Velox Peptides supplies CJC-1295 wo DAC strictly as a research reagent for in vitro use by qualified researchers. It is not a medicinal product and is not for human or veterinary consumption.
What is the CAS number for CJC-1295 wo DAC?
The CAS registry number for CJC-1295 wo DAC is 863288-34-0.
Is CJC-1295 wo DAC legal to buy in the UK?
Yes. CJC-1295 wo DAC is lawful to purchase in the United Kingdom strictly for legitimate in vitro scientific research purposes. It is not a controlled substance under UK law and is not subject to prescription requirements when purchased for research use. Velox Peptides supplies CJC-1295 wo DAC solely as a research reagent to qualified researchers. Buyers are responsible for ensuring all use complies with applicable law and with Velox Peptides’ Research Use Policy.
What is the difference between CJC-1295 with DAC and CJC-1295 without DAC?
The key difference is half-life and binding mechanism. CJC-1295 with DAC (Drug Affinity Complex) contains a maleimidoproprionic acid (MPA) moiety that covalently binds to circulating serum albumin after administration, dramatically extending its half-life to several days in animal models. CJC-1295 without DAC (wo DAC) lacks this moiety and has a shorter half-life more comparable to native GHRH. Velox Peptides supplies the without-DAC formulation — CAS 863288-34-0 — which is suited to research designs requiring more acute, pulsatile stimulation of the GHRH receptor rather than sustained, continuous activation.
How quickly is my order dispatched and delivered?
Orders placed before 2pm on a working day are dispatched the same day via Royal Mail Tracked 24, typically arriving in 1–2 working days, with tracking emailed on dispatch. UK shipping is free over £100, and EU shipping is available.
How do I pay, and is it secure?
We accept Pay by Bank - an instant, secure open-banking payment via Fena, where you authorise the payment in your own banking app and no card details are stored on our site. Manual UK bank transfer is available as a fallback. Orders are dispatched within 24 hours of cleared payment.
Does my order include a certificate of analysis?
Yes. Every order includes a batch-specific Certificate of Analysis documenting third-party HPLC purity and mass-spectrometry identity confirmation, emailed with your order confirmation. Previous batch CoAs are archived in our CoA library.

Compliance notice

For in vitro research use only. CJC-1295 wo DAC is supplied solely as a research reagent for qualified professionals conducting in vitro or animal-model studies. It is not a medicinal product within the meaning of the Human Medicines Regulations 2012. It has not been evaluated by the MHRA or FDA. It is not intended for human or veterinary consumption, diagnosis, treatment, cure, or prevention of any condition. Any use outside lawful scientific research is outside the scope of sale.

Compliance statement. Velox Peptides supplies research reagents for in vitro use by qualified researchers. Every compound is sold strictly as a research reagent. No product is a medicinal product within the meaning of the Human Medicines Regulations 2012. No product has been evaluated by the MHRA or FDA. No product is intended for human or veterinary consumption, diagnosis, treatment, cure, or prevention of any condition. Any use outside lawful scientific research is outside the scope of sale. See our Research Use Policy and MHRA Statement.