Buy GHK-Cu UK – research peptide, HPLC-verified ≥99% purity GHK-Cu PRODUCT IMAGE
HPLC VERIFIED CoA SUPPLIED ≥99% PURITY
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GHK-Cu Copper Tripeptide-1

For in vitro research use only. GHK-Cu is not for human or veterinary consumption, diagnosis, treatment, or prevention of any condition.

GHK-Cu is a tiny naturally occurring molecule made of just three amino acids, found in mammalian blood, where it is bound to a copper atom. In skin cell and animal studies, research has investigated how it affects the genes that produce collagen and elastin - the proteins that give skin and tissue their strength and flexibility.

CAS Number
49557-75-7
Molecular Formula
C₁₄H₂₃CuN₆O₄
HPLC Purity
99% (batch-verified)
Form
Lyophilised powder
Storage
2–8°C, desiccated, protected from light
Classification
Research reagent - in vitro use only
≥99%
HPLC purity
3rd-Party Tested
Independent lab
CoA Every Order
Batch-specific
Tracked 24
Royal Mail UK
Pay by Bank
No card stored

GHK-Cu research overview

GHK-Cu (Glycyl-L-histidyl-L-lysine copper(II)) is a naturally occurring human tripeptide complexed with copper(II) ions. The GHK tripeptide was first isolated from human plasma albumin in the 1970s and subsequently identified in saliva, urine, and wound fluid. Unlike the majority of research reagents in the Velox Peptides catalogue, GHK-Cu is an endogenous compound — it occurs naturally in the human body and its concentrations are known to decline with age — though it is supplied here as a synthesised research reagent at defined purity for controlled experimental conditions.

Research on GHK-Cu has centred on tissue remodelling and gene expression modulation. Cell culture studies have examined its effects on fibroblast activity, specifically collagen and glycosaminoglycan synthesis, and on matrix metalloproteinase (MMP) expression. MMPs are enzymes responsible for breaking down extracellular matrix components; GHK-Cu has been found in several studies to modulate both MMP upregulation and the expression of their endogenous inhibitors (TIMPs), suggesting a regulatory role in matrix turnover. This has made it an active subject in tissue repair biology, skin biology, and dermatological research.

Beyond collagen and tissue repair research, GHK-Cu has been examined for its antioxidant properties — specifically its ability to chelate copper ions and reduce copper-catalysed oxidative damage — and for broader gene expression effects. Studies using DNA microarray and gene expression profiling approaches have identified large numbers of genes potentially modulated by GHK-Cu exposure in cell models, including genes associated with inflammation regulation, neurological function, and cell signalling. Velox Peptides supplies GHK-Cu at 99% HPLC-verified purity as a lyophilised copper tripeptide research reagent. Not for human or veterinary consumption.

Summary paraphrased from the peer-reviewed preclinical literature. For in vitro research use only. For source citations, email support@veloxpeps.com.

📖  GHK-Cu Research Hub
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Compound specifications

Common nameGHK-Cu
Full nameCopper Tripeptide-1
CAS number49557-75-7
Molecular formulaC₁₄H₂₃CuN₆O₄
Molecular weight402.9 g/mol
SequenceGly-His-Lys · Cu²⁺
HPLC purity99% (batch-verified)
AppearanceWhite to off-white lyophilised powder
SolubilityBacteriostatic water, sterile saline
Storage (lyophilised)2–8°C, protected from light
Storage (reconstituted)2–8°C, up to 28 days
Supplied as100mg

Batch testing and certificate of analysis

Every batch of GHK-Cu is third-party HPLC-tested prior to dispatch. Batch documentation is available on request.

Previous batch CoAs are archived in the CoA library. For batch-specific CoA requests prior to purchase, contact support@veloxpeps.com.

Frequently Asked Research-Use Questions

What purity is Velox Peptides GHK-Cu?
GHK-Cu is supplied at 99% HPLC-verified purity. Batch documentation is available on request.
How is GHK-Cu supplied and reconstituted for research use?
GHK-Cu is supplied as a lyophilised powder in sterile single-use vials. For in vitro research use, reconstitution is performed with bacteriostatic water. See the reconstitution calculator for volume calculations based on required concentration.
What is GHK-Cu used for in preclinical research?
GHK-Cu is studied in the peer-reviewed literature across the pathways described in the research overview above. Velox Peptides supplies GHK-Cu strictly as a research reagent for in vitro use by qualified researchers. It is not a medicinal product and is not for human or veterinary consumption.
What is the CAS number for GHK-Cu?
The CAS registry number for GHK-Cu is 49557-75-7.
Is GHK-Cu legal to buy in the UK?
Yes. Research peptides including GHK-Cu are lawful to purchase in the United Kingdom strictly for legitimate in vitro scientific research purposes. They are not controlled substances under UK law and are not subject to prescription requirements when purchased for research use. Velox Peptides supplies GHK-Cu solely as a research reagent to qualified researchers. Buyers are responsible for ensuring all use complies with applicable law and with Velox Peptides’ Research Use Policy.
What is the copper content and structure of GHK-Cu?
GHK-Cu consists of the tripeptide Glycyl-L-histidyl-L-lysine (GHK) complexed with a single copper(II) ion (Cu²⁺). The histidine residue in the tripeptide coordinates copper binding via its imidazole ring nitrogen, giving the complex a defined stoichiometry of one copper ion per peptide molecule. The CAS number for the GHK tripeptide alone is 49557-75-7; the copper complex is CAS 89030-95-5. Both the peptide and its copper complex form are active subjects of research into collagen synthesis, tissue repair biology, and antioxidant biology.
How quickly is my order dispatched and delivered?
Orders placed before 2pm on a working day are dispatched the same day via Royal Mail Tracked 24, typically arriving in 1–2 working days, with tracking emailed on dispatch. UK shipping is free over £100, and EU shipping is available.
How do I pay, and is it secure?
We accept Pay by Bank - an instant, secure open-banking payment via Fena, where you authorise the payment in your own banking app and no card details are stored on our site. Manual UK bank transfer is available as a fallback. Orders are dispatched within 24 hours of cleared payment.
Does my order include a certificate of analysis?
Yes. Every order includes a batch-specific Certificate of Analysis documenting third-party HPLC purity and mass-spectrometry identity confirmation, emailed with your order confirmation. Previous batch CoAs are archived in our CoA library.

For in vitro research use only. GHK-Cu is supplied solely as a research reagent for qualified professionals conducting in vitro or animal-model studies. It is not a medicinal product within the meaning of the Human Medicines Regulations 2012. It has not been evaluated by the MHRA or FDA. It is not intended for human or veterinary consumption, diagnosis, treatment, cure, or prevention of any condition. Any use outside lawful scientific research is outside the scope of sale.

Compliance statement. Velox Peptides supplies research reagents for in vitro use by qualified researchers. Every compound is sold strictly as a research reagent. No product is a medicinal product within the meaning of the Human Medicines Regulations 2012. No product has been evaluated by the MHRA or FDA. No product is intended for human or veterinary consumption, diagnosis, treatment, cure, or prevention of any condition. Any use outside lawful scientific research is outside the scope of sale. See our Research Use Policy and MHRA Statement.