Buy Glutathione UK – research peptide, HPLC-verified ≥99% purity Glutathione PRODUCT IMAGE
HPLC VERIFIED CoA SUPPLIED ≥99.2% PURITY
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- Antioxidant

Glutathione L-Glutathione (Reduced)

For in vitro research use only. Glutathione is not for human or veterinary consumption, diagnosis, treatment, or prevention of any condition.

Glutathione is a small molecule made of three amino acids, found naturally in almost every cell in the body. It acts as one of the cell's main defences against oxidative damage - a process where unstable molecules called free radicals can harm DNA and cell structures. Studies have investigated its role in how cells produce energy and maintain their internal chemical balance.

CAS Number
70-18-8
Molecular Formula
C₁₀H₁₇N₃O₆S
HPLC Purity
99.2% (batch-verified)
Form
Lyophilised powder
Storage
2–8°C, desiccated, protected from light
Classification
Research reagent - in vitro use only
≥99%
HPLC purity
3rd-Party Tested
Independent lab
CoA Every Order
Batch-specific
Tracked 24
Royal Mail UK
Pay by Bank
No card stored

Glutathione research overview

Glutathione (L-Glutathione, reduced form; GSH) is a tripeptide consisting of glutamic acid, cysteine, and glycine (Glu-Cys-Gly), and is the most abundant low-molecular-weight thiol compound in mammalian cells. It is synthesised within cells in two sequential ATP-dependent steps, and maintained in its biologically active reduced form (GSH) through the activity of glutathione reductase using NADPH. Unlike most other research compounds in the Velox Peptides catalogue, glutathione is not a peptide hormone or receptor ligand; it is a metabolic molecule central to fundamental cellular biochemistry, with intracellular concentrations in the millimolar range in healthy cells.

Research on glutathione spans several areas of cell biology. In antioxidant research, GSH acts as a direct free radical scavenger and is an essential cofactor for glutathione peroxidases (GPx enzymes), which detoxify hydrogen peroxide and lipid hydroperoxides. In detoxification research, glutathione serves as the substrate for glutathione S-transferases (GSTs) — a large superfamily of enzymes that conjugate GSH to electrophilic xenobiotics and reactive metabolites, initiating their excretion via the mercapturic acid pathway. In redox signalling research, GSH participates in protein glutathionylation, a reversible post-translational modification that protects protein thiol groups under oxidative conditions.

Glutathione depletion is an active research model in cell biology, with studies using GSH-depleting agents (such as buthionine sulfoximine or diethyl maleate) to examine the cellular consequences of oxidative stress. Exogenous GSH supplementation studies in cell models have examined its ability to restore redox homeostasis, modulate cell viability under oxidative challenge, and influence immune cell function — including T-cell proliferation and cytokine secretion. Velox Peptides supplies L-Glutathione (reduced) at 99.2% HPLC-verified purity in 1500mg vials as a lyophilised research reagent. Not for human or veterinary consumption.

Summary paraphrased from the peer-reviewed preclinical literature. For in vitro research use only. For source citations, email support@veloxpeps.com.

📖  Glutathione Research Hub
Glutathione Research Overview Reconstitution Guide

Compound specifications

Common nameGlutathione
Full nameL-Glutathione (Reduced)
CAS number70-18-8
Molecular formulaC₁₀H₁₇N₃O₆S
Molecular weight307.3 g/mol
Sequenceγ-L-glutamyl-L-cysteinyl-glycine
HPLC purity99.2% (batch-verified)
AppearanceWhite to off-white lyophilised powder
SolubilityBacteriostatic water, sterile saline
Storage (lyophilised)2–8°C, protected from light
Storage (reconstituted)2–8°C, up to 28 days
Supplied as1500mg

Batch testing and certificate of analysis

Every batch of Glutathione is third-party HPLC-tested prior to dispatch. Batch documentation is available on request.

Previous batch CoAs are archived in the CoA library. For batch-specific CoA requests prior to purchase, contact support@veloxpeps.com.

Frequently Asked Research-Use Questions

What purity is Velox Peptides Glutathione?
Glutathione is supplied at 99.2% HPLC-verified purity. Batch documentation is available on request.
How is Glutathione supplied and reconstituted for research use?
Glutathione is supplied as a lyophilised powder in sterile single-use vials. For in vitro research use, reconstitution is performed with bacteriostatic water. See the reconstitution calculator for volume calculations based on required concentration.
What is Glutathione used for in preclinical research?
Glutathione is studied in the peer-reviewed literature across the pathways described in the research overview above. Velox Peptides supplies Glutathione strictly as a research reagent for in vitro use by qualified researchers. It is not a medicinal product and is not for human or veterinary consumption.
What is the CAS number for Glutathione?
The CAS registry number for Glutathione is 70-18-8.
Is Glutathione legal to buy in the UK?
Yes. Glutathione is lawful to purchase in the United Kingdom strictly for legitimate in vitro scientific research purposes. It is not a controlled substance under UK law and is not subject to prescription requirements when purchased for research use. Velox Peptides supplies Glutathione solely as a research reagent to qualified researchers. Buyers are responsible for ensuring all use complies with applicable law and with Velox Peptides’ Research Use Policy.
What is the difference between reduced glutathione (GSH) and oxidised glutathione (GSSG)?
Reduced glutathione (GSH) is the biologically active monomeric form, containing a free thiol (-SH) group on its cysteine residue. Oxidised glutathione (GSSG) is the dimeric disulphide form produced when two GSH molecules are oxidised — this is the form generated when GSH donates electrons to neutralise reactive oxygen species. Cells maintain a high GSH:GSSG ratio (typically >100:1) via glutathione reductase activity. In research, the GSH:GSSG ratio is commonly used as a biomarker of cellular redox status and oxidative stress. Velox Peptides supplies the reduced form (GSH) at 99.2% purity, which is the form active in antioxidant and detoxification reactions.
How quickly is my order dispatched and delivered?
Orders placed before 2pm on a working day are dispatched the same day via Royal Mail Tracked 24, typically arriving in 1–2 working days, with tracking emailed on dispatch. UK shipping is free over £100, and EU shipping is available.
How do I pay, and is it secure?
We accept Pay by Bank - an instant, secure open-banking payment via Fena, where you authorise the payment in your own banking app and no card details are stored on our site. Manual UK bank transfer is available as a fallback. Orders are dispatched within 24 hours of cleared payment.
Does my order include a certificate of analysis?
Yes. Every order includes a batch-specific Certificate of Analysis documenting third-party HPLC purity and mass-spectrometry identity confirmation, emailed with your order confirmation. Previous batch CoAs are archived in our CoA library.

For in vitro research use only. Glutathione is supplied solely as a research reagent for qualified professionals conducting in vitro or animal-model studies. It is not a medicinal product within the meaning of the Human Medicines Regulations 2012. It has not been evaluated by the MHRA or FDA. It is not intended for human or veterinary consumption, diagnosis, treatment, cure, or prevention of any condition. Any use outside lawful scientific research is outside the scope of sale.

Compliance statement. Velox Peptides supplies research reagents for in vitro use by qualified researchers. Every compound is sold strictly as a research reagent. No product is a medicinal product within the meaning of the Human Medicines Regulations 2012. No product has been evaluated by the MHRA or FDA. No product is intended for human or veterinary consumption, diagnosis, treatment, cure, or prevention of any condition. Any use outside lawful scientific research is outside the scope of sale. See our Research Use Policy and MHRA Statement.