Semax Semax PRODUCT IMAGE
HPLC VERIFIED COA SUPPLIED ≥99% PURITY
— Cognitive

Semax ACTH(4-7) Pro-Gly-Pro Analogue

For in vitro research use only. Semax is not for human or veterinary consumption, diagnosis, treatment, or prevention of any condition.

Semax is a synthetic peptide made up of 7 amino acids, based on a fragment of ACTH (Adrenocorticotropic Hormone — a naturally occurring stress hormone). A short chemical tail has been added to make it more stable and longer-lasting inside biological systems. Preclinical studies have investigated its effects on BDNF (Brain-Derived Neurotrophic Factor — a protein that supports brain cell growth and survival) levels in neuronal tissue.

CAS Number
80714-61-0
Molecular Formula
C₃₇H₅₁N₉O₁₀S
HPLC Purity
99% (batch-verified)
Form
Lyophilised powder
Storage
2–8°C, desiccated, protected from light
Classification
Research reagent — in vitro use only

Research overview

Semax is a synthetic 7-amino-acid peptide based on a segment of ACTH (Adrenocorticotropic Hormone — a hormone the body naturally produces in response to stress). A stabilising chemical tail (Pro-Gly-Pro) has been added to the molecule to slow its breakdown and extend how long it remains active in biological systems. Preclinical studies have measured increased BDNF (Brain-Derived Neurotrophic Factor — a protein that supports brain cell growth, survival, and the formation of new connections between cells) expression in neuronal tissue. Research has also examined potential neuroprotective effects (the ability to protect nerve cells from damage) in animal models of experimentally induced brain ischaemia (a state where brain tissue is temporarily deprived of blood flow). Semax has been widely studied in neuroscience research, particularly in Eastern European scientific institutions. For research use only. Not for human or veterinary consumption.

Summary paraphrased from the peer-reviewed preclinical literature. Full citations will be available in the research library. For in vitro research use only.

Compound specifications

Common nameSemax
Full nameACTH(4-7) Pro-Gly-Pro Analogue
CAS number80714-61-0
Molecular formulaC₃₇H₅₁N₉O₁₀S
Molecular weight813.9 g/mol
SequenceMEHFPGP
HPLC purity99% (batch-verified)
AppearanceWhite to off-white lyophilised powder
SolubilityBacteriostatic water, sterile saline
Storage (lyophilised)2–8°C, protected from light
Storage (reconstituted)2–8°C, up to 28 days
Supplied as10mg

Batch testing and certificate of analysis

Every batch of Semax is third-party HPLC-tested prior to dispatch. A batch-specific certificate of analysis documenting HPLC purity, mass spectrometry confirmation, and appearance is supplied with every order.

Previous batch CoAs are archived in the CoA library. For batch-specific CoA requests prior to purchase, contact veloxpeps@gmail.com.

Frequently Asked Research-Use Questions

What purity is Velox Peptides Semax?
Semax is supplied at 99% HPLC-verified purity. A certificate of analysis is provided with every order. Every batch is third-party tested before dispatch.
How is Semax supplied and reconstituted for research use?
Semax is supplied as a lyophilised powder in sterile single-use vials. For in vitro research use, reconstitution is performed with bacteriostatic water. See the reconstitution calculator for volume calculations based on required concentration.
What is Semax used for in preclinical research?
Semax is studied in the peer-reviewed literature across the pathways described in the research overview above. Velox Peptides supplies Semax strictly as a research reagent for in vitro use by qualified researchers. It is not a medicinal product and is not for human or veterinary consumption.
What is the CAS number for Semax?
The CAS registry number for Semax is 80714-61-0. This identifier is listed on every batch certificate of analysis supplied with orders.

For in vitro research use only. Semax is supplied solely as a research reagent for qualified professionals conducting in vitro or animal-model studies. It is not a medicinal product within the meaning of the Human Medicines Regulations 2012. It has not been evaluated by the MHRA or FDA. It is not intended for human or veterinary consumption, diagnosis, treatment, cure, or prevention of any condition. Any use outside lawful scientific research is outside the scope of sale.

Compliance statement. Velox Peptides supplies research reagents for in vitro use by qualified researchers. Every compound is sold strictly as a research reagent. No product is a medicinal product within the meaning of the Human Medicines Regulations 2012. No product has been evaluated by the MHRA or FDA. No product is intended for human or veterinary consumption, diagnosis, treatment, cure, or prevention of any condition. Any use outside lawful scientific research is outside the scope of sale. See our Research Use Policy and MHRA Statement.