Growth
GHRP-6 Growth Hormone-Releasing Hexapeptide
Growth
GHRP-6 research overview
- CAS Number
- 87616-84-0
- Molecular Formula
- C₄₆H₅₆N₁₂O₆
- HPLC Purity
- ≥99% (batch-verified)
- Form
- Lyophilised powder
- Storage
- 2–8°C, desiccated, protected from light
- Classification
- Research reagent - in vitro use only
GHRP-6 (growth hormone-releasing peptide-6) is a synthetic hexapeptide and one of the first-described growth hormone secretagogues. It is an agonist of the growth hormone secretagogue receptor (GHS-R1a), now known as the ghrelin receptor, and remains a standard reference ligand for that receptor.
GHRP-6 was developed by Cyril Bowers and colleagues in the 1980s from met-enkephalin analogues, before the receptor it acts on had been identified. The peptide contains two D-amino acids (D-Trp and D-Phe) that contribute to its potency and stability in experimental systems. The receptor, GHS-R1a, was cloned in 1996, and its endogenous ligand ghrelin was discovered in 1999.
In cell-based research, GHRP-6 is used in GHS-R1a binding and functional assays, where receptor activation is coupled through Gq/11 to phospholipase C and intracellular calcium release. It is used in pituitary cell cultures and as a positive control when characterising newer secretagogues and ghrelin-receptor antagonists.
GHRP-6 belongs to the same family as GHRP-2 and Ipamorelin, and researchers frequently compare the three, as well as studying them alongside GHRH analogues such as CJC-1295 and Sermorelin, which act on a different receptor. Velox Peptides supplies GHRP-6 at ≥99% HPLC-verified purity as a 10mg lyophilised research reagent. Not for human or veterinary consumption.
Summary paraphrased from the peer-reviewed preclinical literature. For in vitro research use only. For source citations, email support@veloxpeps.com.
GHRP-6 Research Hub
Technical data
Compound specifications
| Common name | GHRP-6 (Growth hormone-releasing peptide-6, GHRP6) |
|---|---|
| Full name | Growth hormone-releasing peptide-6 |
| CAS number | 87616-84-0 |
| Molecular formula | C₄₆H₅₆N₁₂O₆ |
| Molecular weight | 873.0 g/mol |
| Sequence | His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 |
| HPLC purity | ≥99% (batch-verified) |
| Appearance | White to off-white lyophilised powder |
| Solubility | Bacteriostatic water, sterile saline |
| Storage (lyophilised) | 2–8°C, protected from light |
| Storage (reconstituted) | 2–8°C, up to 28 days |
| Supplied as | 10mg |
Purity & documentation
Batch testing and certificate of analysis
Every batch of GHRP-6 is third-party HPLC-tested prior to dispatch. Batch documentation is available on request.
Previous batch CoAs are archived in the CoA library. For batch-specific CoA requests prior to purchase, contact support@veloxpeps.com.
Delivery & payment
Buying GHRP-6 in the UK
GHRP-6 is sold by Velox Peptides (CRP Labs Ltd, UK company no. NI738125) and dispatched from the UK. Choose a vial size, pay on one page, and your order is dispatched the next working day.
- Delivery: Royal Mail Tracked 24 (1–2 working days, £5.99, free over £100) or Tracked 48 (2–3 working days, £3.80). See shipping.
- Payment: Pay by Bank through FCA-authorised open banking, or bank transfer. No card details needed.
- Testing: See the batch testing details above and past reports in the CoA library.
- Research use only: Supplied as a research reagent for in vitro use. Not for human or veterinary consumption. See our Research Use Policy.
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Compliance notice
For in vitro research use only. GHRP-6 is supplied solely as a research reagent for qualified professionals conducting in vitro or animal-model studies. It is not a medicinal product within the meaning of the Human Medicines Regulations 2012. It has not been evaluated by the MHRA or FDA. It is not intended for human or veterinary consumption, diagnosis, treatment, cure, or prevention of any condition. Any use outside lawful scientific research is outside the scope of sale.
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