STACK IMAGE - RESEARCH BUNDLE · 2 COMPOUNDS
Neuropeptide Dual Research Bundle
Semax + Selank
Semax10mg£34.99Selank10mg£39.99
£74.98
£55.98
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- Cognitive
Selank Synthetic Heptapeptide (TKPRPGP)
For in vitro research use only. Selank is not for human or veterinary consumption, diagnosis, treatment, or prevention of any condition.
Selank is a synthetic peptide made up of 7 amino acids, based on a fragment of tuftsin - a small protein naturally involved in immune function. In rodent studies, researchers have observed calmer animal behaviour without the sedation (drowsiness) typically seen with classical anxiety-reducing compounds, making it a distinctive tool for studying stress and anxiety pathways in the brain.
- CAS Number
- 129954-34-3
- Molecular Formula
- C₃₃H₅₇N₉O₁₁
- HPLC Purity
- ≥99% (batch-verified)
- Form
- Lyophilised powder
- Storage
- 2–8°C, desiccated, protected from light
- Classification
- Research reagent - in vitro use only
≥99%
HPLC purity
3rd-Party Tested
Independent lab
CoA Every Order
Batch-specific
Tracked 24
Royal Mail UK
Pay by Bank
No card stored
Research overview
Selank is a synthetic heptapeptide with the amino acid sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP). It was developed as a metabolically stable analogue of tuftsin (Thr-Lys-Pro-Arg), an endogenous immunomodulatory tetrapeptide derived from immunoglobulin G. The appended Pro-Gly-Pro tripeptide at the C-terminus inhibits degradation by peptidases that would otherwise rapidly cleave the parent tuftsin sequence, extending the half-life of the compound in experimental conditions and making it a more tractable tool for research applications.
In preclinical animal research, Selank has been studied primarily in behavioural neuroscience models. Studies have examined its effects in anxiety models including the elevated plus maze, open field test, and conflict-based paradigms in rodents, with researchers investigating its interaction with GABAergic neurotransmission pathways. It has also been examined in relation to enkephalin metabolism — enkephalins are endogenous opioid neuropeptides involved in pain and stress response — with some rodent studies reporting that Selank inhibits enzymes responsible for enkephalin breakdown, thereby extending enkephalin activity in the synapse.
Beyond anxiety models, Selank has been studied for effects on memory consolidation and learning paradigms in rodents, and for its interaction with brain-derived neurotrophic factor (BDNF) expression. Its tuftsin-derived structure has prompted immunological research examining its effects on T-cell function and cytokine balance in preclinical models. Velox Peptides supplies Selank at ≥99% HPLC-verified purity as a lyophilised research reagent for in vitro use by qualified researchers. Not for human or veterinary consumption.
Summary paraphrased from the peer-reviewed preclinical literature. For in vitro research use only. For source citations, email support@veloxpeps.com.
Compound specifications
| Common name | Selank |
|---|---|
| Full name | Synthetic Heptapeptide (TKPRPGP) |
| CAS number | 129954-34-3 |
| Molecular formula | C₃₃H₅₇N₉O₁₁ |
| Molecular weight | 751.9 g/mol |
| Sequence | TKPRPGP |
| HPLC purity | ≥99% (batch-verified) |
| Appearance | White to off-white lyophilised powder |
| Solubility | Bacteriostatic water, sterile saline |
| Storage (lyophilised) | 2–8°C, protected from light |
| Storage (reconstituted) | 2–8°C, up to 28 days |
| Supplied as | 10mg |
Batch testing and certificate of analysis
Every batch of Selank is third-party HPLC-tested prior to dispatch. Batch documentation is available on request.
Previous batch CoAs are archived in the CoA library. For batch-specific CoA requests prior to purchase, contact support@veloxpeps.com.
Stacks containing Selank
Related compounds
Frequently Asked Research-Use Questions
What purity is Velox Peptides Selank?
Selank is supplied at ≥99% HPLC-verified purity. Batch documentation is available on request.
How is Selank supplied and reconstituted for research use?
Selank is supplied as a lyophilised powder in sterile single-use vials. For in vitro research use, reconstitution is performed with bacteriostatic water. See the reconstitution calculator for volume calculations based on required concentration.
What is Selank used for in preclinical research?
Selank is studied in the peer-reviewed literature across the pathways described in the research overview above. Velox Peptides supplies Selank strictly as a research reagent for in vitro use by qualified researchers. It is not a medicinal product and is not for human or veterinary consumption.
What is the CAS number for Selank?
The CAS registry number for Selank is 129954-34-3.
Is Selank legal to buy in the UK?
Yes. Research peptides including Selank are lawful to purchase in the United Kingdom strictly for legitimate in vitro scientific research purposes. They are not controlled substances under UK law and are not subject to prescription requirements when purchased for research use. Velox Peptides supplies Selank solely as a research reagent to qualified researchers. Buyers are responsible for ensuring all use complies with applicable law and with Velox Peptides’ Research Use Policy.
What is the structural relationship between Selank and tuftsin?
Selank (TKPRPGP) is a synthetic heptapeptide analogue of tuftsin (TKPR), an endogenous immunomodulatory tetrapeptide derived from the Fc region of immunoglobulin G. Selank was developed by appending a Pro-Gly-Pro (PGP) tripeptide to the C-terminus of tuftsin, which substantially increases resistance to enzymatic degradation compared to the parent compound. This modification extends the compound’s suitability for experimental research while retaining its interaction with systems associated with the tuftsin parent structure.
How quickly is my order dispatched and delivered?
Orders placed before 2pm on a working day are dispatched the same day via Royal Mail Tracked 24, typically arriving in 1–2 working days, with tracking emailed on dispatch. UK shipping is free over £80, and EU shipping is available.
How do I pay, and is it secure?
We accept Pay by Bank - an instant, secure open-banking payment via Fena, where you authorise the payment in your own banking app and no card details are stored on our site. Manual UK bank transfer is available as a fallback. Orders are dispatched within 24 hours of cleared payment.
Does my order include a certificate of analysis?
Yes. Every order includes a batch-specific Certificate of Analysis documenting third-party HPLC purity and mass-spectrometry identity confirmation, emailed with your order confirmation. Previous batch CoAs are archived in our CoA library.
Compliance notice
For in vitro research use only. Selank is supplied solely as a research reagent for qualified professionals conducting in vitro or animal-model studies. It is not a medicinal product within the meaning of the Human Medicines Regulations 2012. It has not been evaluated by the MHRA or FDA. It is not intended for human or veterinary consumption, diagnosis, treatment, cure, or prevention of any condition. Any use outside lawful scientific research is outside the scope of sale.
