Bioregulator
Epitalon Epithalon · AEDG Tetrapeptide
Bioregulator
Epitalon research overview
- CAS Number
- 307297-39-8
- Molecular Formula
- C₁₄H₂₂N₄O₉
- HPLC Purity
- ≥99% (batch-verified)
- Form
- Lyophilised powder
- Storage
- 2–8°C, desiccated, protected from light
- Classification
- Research reagent - in vitro use only
Epitalon (also written Epithalon) is a synthetic tetrapeptide with the sequence Ala-Glu-Asp-Gly (AEDG). It was designed as a defined, synthetic counterpart to epithalamin, a peptide extract of the pineal gland, and is one of the most widely studied short peptide bioregulators in the preclinical literature.
Epitalon was developed at the St. Petersburg Institute of Bioregulation and Gerontology, where short peptides were synthesised on the basis of the amino-acid composition of tissue extracts. At four residues and a molecular weight of 390.35 g/mol it is among the smallest peptides in the catalogue, and it is highly water-soluble.
In cell-based research, Epitalon is best known from studies in human somatic cell cultures reporting induction of telomerase catalytic subunit expression and telomere elongation. Other in vitro work has examined its interaction with chromatin and promoter regions, and its effects on gene expression in fibroblast and retinal cell models.
Animal-model studies have examined Epitalon in the context of pineal function and circadian markers. Researchers often study it alongside other short peptide bioregulators and antioxidant-pathway compounds. Velox Peptides supplies Epitalon at ≥99% HPLC-verified purity as a 10mg lyophilised research reagent. Not for human or veterinary consumption.
Summary paraphrased from the peer-reviewed preclinical literature. For in vitro research use only. For source citations, email support@veloxpeps.com.
Epitalon Research Hub
Technical data
Compound specifications
| Common name | Epitalon (Epithalon, Epithalone) |
|---|---|
| Full name | Ala-Glu-Asp-Gly tetrapeptide |
| CAS number | 307297-39-8 |
| Molecular formula | C₁₄H₂₂N₄O₉ |
| Molecular weight | 390.35 g/mol |
| Sequence | Ala-Glu-Asp-Gly |
| HPLC purity | ≥99% (batch-verified) |
| Appearance | White to off-white lyophilised powder |
| Solubility | Bacteriostatic water, sterile saline |
| Storage (lyophilised) | 2–8°C, protected from light |
| Storage (reconstituted) | 2–8°C, up to 28 days |
| Supplied as | 10mg |
Purity & documentation
Batch testing and certificate of analysis
Every batch of Epitalon is third-party HPLC-tested prior to dispatch. Batch documentation is available on request.
Previous batch CoAs are archived in the CoA library. For batch-specific CoA requests prior to purchase, contact support@veloxpeps.com.
Delivery & payment
Buying Epitalon in the UK
Epitalon is sold by Velox Peptides (CRP Labs Ltd, UK company no. NI738125) and dispatched from the UK. Choose a vial size, pay on one page, and your order is dispatched the next working day.
- Delivery: Royal Mail Tracked 24 (1–2 working days, £5.99, free over £100) or Tracked 48 (2–3 working days, £3.80). See shipping.
- Payment: Pay by Bank through FCA-authorised open banking, or bank transfer. No card details needed.
- Testing: See the batch testing details above and past reports in the CoA library.
- Research use only: Supplied as a research reagent for in vitro use. Not for human or veterinary consumption. See our Research Use Policy.
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Compliance notice
For in vitro research use only. Epitalon is supplied solely as a research reagent for qualified professionals conducting in vitro or animal-model studies. It is not a medicinal product within the meaning of the Human Medicines Regulations 2012. It has not been evaluated by the MHRA or FDA. It is not intended for human or veterinary consumption, diagnosis, treatment, cure, or prevention of any condition. Any use outside lawful scientific research is outside the scope of sale.
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