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Selank vs Semax — comparison summary

This page compares Selank and Semax across mechanism of action, receptor targets, molecular weight, solubility and research focus, for in vitro research use only.

Selank

An anxiolytic-studied peptide derived from tuftsin.

Mechanism
A synthetic analogue of the immunopeptide tuftsin, studied for anxiolytic and immunomodulatory activity in preclinical models.
Receptor targets
GABA / serotonergic modulation; tuftsin pathway.
Molecular weight
751.9 g/mol
Solubility
Highly water-soluble
Research focus
Researched for stress, anxiety and immune-modulation models.

Semax

A nootropic peptide studied for neuroprotection.

Mechanism
A synthetic ACTH(4-10) fragment analogue studied for BDNF modulation and neuroprotection in preclinical models.
Receptor targets
Melanocortin / BDNF-linked pathways (no single classical receptor).
Molecular weight
813.9 g/mol
Solubility
Highly water-soluble
Research focus
Studied for cognition, focus and neuroprotection in animal models.
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