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CJC-1295 (no DAC) vs Tesamorelin — comparison summary

This page compares CJC-1295 (no DAC) and Tesamorelin across mechanism of action, receptor targets, molecular weight, solubility and research focus, for in vitro research use only.

CJC-1295 (no DAC)

A GHRH analogue studied for pulsatile growth-hormone release.

Mechanism
A modified fragment of growth-hormone-releasing hormone (GHRH 1-29) that stimulates the pituitary to release growth hormone in preclinical models.
Receptor targets
GHRH receptor (GHRH-R) on pituitary somatotrophs.
Molecular weight
3367.9 g/mol
Solubility
Water-soluble
Research focus
Frequently studied alongside ghrelin-receptor agonists (e.g. Ipamorelin) for synergistic GH release.

Tesamorelin

A stabilised GHRH analogue with extended activity.

Mechanism
A GHRH analogue modified for greater stability, studied for sustained GH-axis stimulation in preclinical models.
Receptor targets
GHRH receptor (GHRH-R).
Molecular weight
5135.9 g/mol
Solubility
Water-soluble
Research focus
Researched for visceral-fat and metabolic endpoints in the literature.
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