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BPC-157 vs GHK-Cu — comparison summary

This page compares BPC-157 and GHK-Cu across mechanism of action, receptor targets, molecular weight, solubility and research focus, for in vitro research use only.

BPC-157

A stable gastric pentadecapeptide widely studied for tissue repair.

Mechanism
A synthetic 15-amino-acid fragment of a gastric protein studied for promoting angiogenesis (new blood-vessel formation) and tissue repair in preclinical models.
Receptor targets
Acts largely through growth-factor and nitric-oxide pathways; no single named receptor — modulates the VEGFR2 / NO system.
Molecular weight
1419.5 g/mol
Solubility
Highly water-soluble
Research focus
Extensively studied in vitro and in animal models for tendon, ligament, muscle and gut-lining repair.

GHK-Cu

A copper-binding tripeptide central to skin-repair research.

Mechanism
A naturally occurring tripeptide that binds copper and is studied for collagen synthesis, antioxidant and skin-remodelling activity in fibroblast models.
Receptor targets
No single receptor — acts via copper delivery and gene-expression modulation.
Molecular weight
403.9 g/mol
Solubility
Highly water-soluble
Research focus
One of the most-studied cosmetic peptides for skin firmness and repair in vitro.
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